Clinical Studies

The OSF Medical Group - Clinical Research Center is located at the OSF Center for Health - Route 91 in Peoria, Illinois. They are devoted to offering medical group patients access to new forms of treatment for chronic conditions such as Type 2 diabetes, osteoporosis for men, and high blood pressure. Their main goal is to be involved in studies that focus on finding the best treatments currently available for our patients. The OSF Medical Group - Clinical Research Center continues to actively partner with quality pharmaceutical companies and they provide patients with access to medications and national and international studies that can not be obtained elsewhere. This endeavor is directly related to the OSF Mission, "to serve persons with the greatest care and love."

You may qualify for a study if you can answer Yes to these questions.
 

Type 2 diabetes using an FDA approved medication Aliskiren.

This study is a randomized, double-blind, placebo-controlled, parallel-group study to determine whether, patients with type 2 diabetes at high risk for cardiovascular and renal events, aliskiren, on top of conventional treatment, reduces cardiovascular and renal morbidity and mortality. In order to qualify patients must be 35 years of age or older and have Type 2 diabetes. Patients will receive, at no cost to them or their insurance, the study medication, all study-related physician visits, and all protocol-related labs. During this 48 week study there will be 22 office visits to closely monitor the response to this therapy.

1. Patient is NOT pregnant or nursing.
2. Patient is 35 years of age or older.
3. Patient has NO history of any cardiovascular event (stroke, transient ischemic cerebral attack, MI, unstable angina, CABG, percutaneaous coronary intervention) 3 months prior to visit.
4. Patient has NOT had any malignancy in the last 5 years, other than basal cell or squamous cell skin cancer.

High blood pressure for men and women who are 18 years to 75 years of age.

To qualify for this study you must have a diagnosis of high blood pressure, and currently or not currently on medication. Qualifying will be given study medication to treat high blood pressure while being closely monitored by a physician. The duration of the study is 9 weeks with 7 clinic visits. Patients will receive study medication, protocol-specific testing and clinic visits at no cost.

1. Patient is older than 18 years old, up to and including 75
2. Patients with mild-to moderate uncomplicated essential hypertension, untreated or currently taking antihypertensive therapy
3. Patient is not Type 1 or 2 diabetes mellitus
4. Patient does not have a history of heart failure and no history of malignancy (except non Melanoma skin cancer) within the past 5 years

Type 2 Diabetes Mellitus using FDA approved Exenatide (Byetta) & investigational injectable medication.

This study is for Type 2 Diabetes. The patient must be on Metformin >1500 mg/day and/or Pioglitazone >30 mg/day or Rosiglitazone >4 mg/day for at least 12 weeks. This is a one year study and consists of 11 office visits.

1. Patient is 18 to 75 years of age
2. Patient has Type 2 diabetes
3. Patient has HbA1c of >7.0% up to 10.0% at time of screening
4. BMI of >25 but less than 45 kg/m2 

Type 2 diabetes study using FDA approval oral medications.

This study is for Type 2 diabetes.  The patient must be naive to all diabetes therapies, OR stop taking diabetes therapy for at least eight weeks OR on either Metformin or another oral medication in the sulfonylurea class.  This is a one year study and consists of 11 office visits.

1. Patient is 18 to 78 years of age
2. Patient has been newly diagnosed or current diagnosis of Type 2 diabetes
3. Patient has HbA1c of 7.0% up to 9.0% at time of screening

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Compensation is provided for time and travel.

OSF Medical Group-Clinical Research Center
8600 North State Route 91, Suite #130
Peoria, Illinois 61615
Email: osfmgresearch@osfhealthcare.org
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